Hong Kong Med J 2006;12:394-7. Research suggests there are beneficial compounds in rhubarb that may fight cancer, lower cholesterol, reduce inflammation, lower blood pressure and protect eye and brain health. It also reduced the length of the hospital stay and the need for IV fluids better than just antibiotics (Ceftizoxime sodium or Levofloxacin) [35]. Chinese rhubarb added to a Chinese remedy (Compound Tong Jiang Oral Liquid), improved memory and had antioxidant effects in senile people. However, sound clinical evidence for its use is lacking. SelfDecode is a personalized health report service, This list does not cover all possible side effects. Cureus 2021;13(10):e18419. (Chinese Journal of Modern Developments in Traditional Medicine) 1988;8(6):344-6, 324-5. Note: Results may vary about any product effectiveness. Bi ZQ, Kang ZQ, and Zheng FL. Rhubarb is a type of laxative called a stimulant laxative. 2007 Mar-Apr;14(2):270-83. Multiple human studies have shown that Siberian rhubarb extract significantly reduces all 11 of the recognized menopausal symptoms. I am currently continuing at SunAgri as an R&D engineer. Although it can be eaten raw, rhubarb tends to be too tart this way, and its usually best when cooked with plenty of sugar. View abstract. Zhong.Xi.Yi.Jie.He.Za Zhi. Side effects might include stomach pain, diarrhea, nausea, vomiting, and cramps. Wang, Z., Wang, G., Xu, H., and Wang, P. [Anti-herpes virus action of ethanol-extract from the root and rhizome of Rheum officinale Baill.]. [Long-term treating effects of rhubarb and captopril in delaying the progression of renal failure]. Wilson M, Konda V, Heidt K, Rathinasabapathy T, Desai A, Komarnytsky S. Int J Mol Sci. 2021 Jan 21;22(3):1032. doi: 10.3390/ijms22031032. Chen, X. and Ran, R. [Rhubarb decoction prevents intestinal bacterial translocation during necrotic pancreatitis]. There is some concern that black cohosh might decrease how well cisplatin (Platinol-AQ) works for cancer. Introduction 2016 Aug;46(8):677-82. Renggli, H. [Gingivitis-and plaque-inhibiting action of Pyralvex Berna and its components]. [Preliminary study of Rheum enema in the treatment of chronic renal failure]. View abstract. This means if you can click on the link and purchase an item, we will receive a commission. 1993;73(6):343-5, 380-1. Note that each number in parentheses [1, 2, 3, etc.] Theres also a chance it could interact with other medications. Chinese Journal of Modern Developments in Traditional Medicine 1987;7(1):21-3, 4. Evidences for antiosteoporotic and selective estrogen receptor modulator activity of silymarin compared with ethinylestradiol in ovariectomized rats. In Canada, you may report side effects to Health Canada at 1-866-234-2345. Unauthorized use of these marks is strictly prohibited. The adverse effects most often reported were hypersensitivity or rash, gastrointestinal problems like bloating and diarrhea, and nervous system problems like headaches. Side Effects of Eating Too Many Rhubarbs (1) Too Much Dietary Fiber Is Bad For Stomach Consuming rhubarb on a regular and moderate basis has been found to be very beneficial for our stomach and helps in keeping our digestive system healthy. This remedy may allow for the dosage of steroids to be lowered while achieving equal anti-inflammatory benefits [20]. You can also drag and drop the file into the provided field. 2008 Nov-Dec;14(6):32-8. but is for informational and educational purposes alone. You should not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. View abstract. Complement Ther Med. While some of these side effects like discolored urine are harmless, some others are mild. In another trial of 89 critically-ill children, a Chinese herbal remedy (Fuan Liquid) added to conventional drugs successfully reduced gut dysfunction. Long-term use or use in higher doses can lead to bone loss, muscular weakness, irregular heart rhythm, and potassium loss. View abstract. Yan, M., Zhang, L. Y., Sun, L. X., Jiang, Z. Nephrol.Dial.Transplant. The efficacy of ERr 731(), a commercially available extract isolated from Rheum rhaponticum, in terms of menopausal complaints like hot flushes, depression, anxiety and vaginal dryness has been proven in a two-year clinical study. Rhubarb has been studied for the management of GI and renal function disorders, and for the treatment of hyperlipidemia, cancer, and acute ischemic stroke. In a clinical trial of 80 people, 20 mg/kg rhubarb reduced the incidence of lung toxicity, improved lung function, and reduced levels of inflammatory substances (TGF-beta1 and IL-6) [53]. Rhapontic Rhubarb Root extract Microcrystalline Cellulose Stearic Acid Silica Sodium Pros The product could help you ease the symptoms of menopause It might be able to reduce pain, anxiety, restlessness, and other commonly associated symptoms It could help you get through the episodes of hot flashes View abstract. Always consult your doctor before using any supplements. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Acute respiratory distress syndrome (ARDS). [Retention enema with Rheum decoction in treating renal failure]. According to a meta-analysis of 16 clinical trials with over 900 people, rhubarb used with standard treatment is effective and safe for reducing pancreatic inflammation [25]. These compounds are not absorbed in the intestine and reach the colon unchanged. If you are experiencing night sweats or any other concerning symptoms while taking Estroven Complete or any other supplement, it is recommended that you speak with your healthcare provider for further guidance. In conclusion, the observations from previous trials regarding the endometrial safety of ERr 731() have been supported by our experimental findings that exclude a stimulatory activity on proliferation in the uterus in a long-term administration in the young adult rat but no effect on the bone mineral density could be observed. We address the endometrial safety of a rhapontic extract and test potential effects in the bone. Chang JL, Montalto MB, Heger PW, Thiemann E, Rettenberger R, Wacker J. Integr Med (Encinitas). Zhu, Y. Chir Dent.Fr. Rhubarb can be found in various forms, usually made from the roots and rhizomes of Chinese rhubarb [3, 4]: The below doses may not apply to you personally. Am J Chin Med 2005;33(6):839-850. Rhubarb also contains fiber, which might help reduce cholesterol levels and affect stomach conditions. "Water pills" can also decrease potassium levels. Long-term application of ERr 731 delivered no indication for any proliferation in the uterus. I love to write and share science related Stuff Here on my Website. Stay up to date with the latest health information from experts/contributors at Consumer Health Digest. Rash. Researchers found 12 weeks of treatment with a pill containing extract of Rheum rhaponticum, the vegetable more commonly known as rhubarb, significantly reduced the frequency and severity of hot. It includes rhaponticin and desoxyrhaponticin, which are able to stimulate estrogen receptors. tic r-pn-tik. Nutrition Research 1998;18(5):893-903. Other anthraquinone compounds such as aloe-emodin, emodin, and rhein have antibacterial properties. Epub 2009 Oct 4. In a clinical trial of 60 people with digestive tract bleeding and fever, taking ground Chinese rhubarb (3 g, 3-4x/day) with ground Chinese ginseng (sanchi powder) boosted recovery. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Anti-allergic effects of stilbene components from Rhei undulati Rhizoma (dried rhizome of Rheum undulatum cultivated in Korea). View abstract. 2015 Dec;23(6):794-801. You can take it at any time of the day you choose. A clinical study on compound da huang (radix et Rhizoma rhei) preparations for improvement of senile persons' memory ability. Aleksa is passionate about herbal pharmacy, nutrition, and functional medicine. Zhong.Xi.Yi.Jie.He.Za Zhi. Wu, C. X. The health effects of the other forms of rhubarb have not been studied extensively. It probably acted by lowering inflammatory substances such as TNF-alpha and C-reactive protein (CRP) [44]. A meta-analysis of 27 animal studies determined Chinese rhubarb may help reduce organ damage from blood poisoning. One such compound, emodin, is effective against Staphylococcus aureus (even antibiotic-resistant strains), the bacteria that causes staph infections [8]. A: If you are curious to know whether Estroven Complete menopause supplement causes night sweats within the first couple of months, as with any supplement or medication, side effects can occur and may vary from person to person. Ethnobotanical Uses, Phytochemistry and Pharmacology of Different Rheum Species (Polygonaceae): A Review. Disclaimer. Treating Psoriasis With Biologics: What to Know, Symptoms of menopause. In addition . Pregnant women should avoid it while others should consult their doctor before supplementing. Ali R, Irfan M, Akram U, et al. We do not aim to diagnose, treat, cure or prevent any illness or disease. 2020;52:102476. FOIA Zhou Y, Wang L, Huang X, Li H, Xiong Y. Add-on effect of crude rhubarb to somatostatin for acute pancreatitis: A meta-analysis of randomized controlled trials. Stimulation of ER has been shown to elicit beneficial estrogen-like activities and reduce adverse side effects. In a study with over 1,000 patients with sepsis, Chinese rhubarb reduced fungal infections, especially when combined with adequate nutrition (via stomach tubes or IV) [37]. Russia supplied and controlled the export of the dried root, thus controlling its price. Due to its laxative effects, rhubarb may cause stomach discomfort, nausea, vomiting or diarrhea in certain people. View abstract. Dr Oz: Menopause Survival Smoothie Recipe. American College of Gastroenterology guideline: management of acute pancreatitis. Zhongguo Zhong.Yao Za Zhi. After 84 days, the rhubarb extract reduced menopausal symptoms by 60%. 2) helped people undergoing gallbladder removal surgery recover gut functionality more quickly. View abstract. Bi, Z. Q. Furthermore, no impact of the two administered ERr 731() doses on the E2 deprivation-induced bone loss has been evident at the end of the study. Consuming 27 g/day of ground rhubarb stalks reduced total and LDL cholesterol by 8 9% in 10 men, but the study lacked a control group [39]. View abstract. The special extract ERr 731 from the roots of rhapontic rhubarb has been regularly prescribed for women with menopausal symptoms since 1993. Rhubarb root and rhizome-based Chinese herbal prescriptions for acute ischemic stroke: a systematic review and meta-analysis. Research shows evidence for the effectiveness of this plant in treating menopause symptoms. The .gov means its official. More than 900 milligrams a day of black cohosh is considered an overdose. Ji, S. M., Li, L. S., and Ji, D. X. Nutrition Reserach 1993;13:1017-1024. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Design: Three hundred sixty-three menopausal women with menopausal . Women who have or have had breast cancer or uterine cancer. However, you shouldnt interpret them as supportive of any health benefit. Hasper I, Ventskovskiy BM, Rettenberger R, Heger PW, Riley DS, Kaszkin-Bettag M. Long-term efficacy and safety of the special extract ERr 731 of Rheum rhaponticum in perimenopausal women with menopausal symptoms. [A preliminary study on the effect of a single Rheum officinale in heavy doses in the treatment of acute icteric hepatitis]. The information contained in this website is provided for general informational purposes only. [Clinical evaluation of crude rhubarb powder and cimetidine in upper gastrointestinal bleeding]. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Clinical study on rhubarb extract tablet in treating simple obesity. Tian, J., Chen, X. M., and Li, L. S. [Effects of Cordyceps sinensis, rhubarb and serum renotropin on tubular epithelial cell growth]. 1993;13(2):71-3, 67. Rhubarb can cause some side effects such as stomach and intestinal pain, watery diarrhea, nausea, vomiting, rash, and uterine contractions. from 1750 to 1850 Russia was making a fortune from trading rhubarb root through st Petersburg to europe via the baltic. Hu J, Li P, Zhang T. Rhubarb combined with trypsin inhibitor for severe acute pancreatitis: a systematic review and meta-analysis. Your use of this website indicates your agreement to this websites published terms of use and all site policies. Zhong.Xi.Yi.Jie.He.Xue.Bao. Such symptoms include: hot flashes weight gain low metabolism mood shifts night sweats difficulty concentrating The. Rhubarb rhizome and root are likely safe in the amounts present in food and possibly safe as nutritional supplements, used in adequate amounts. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). - 1 tbsp flaxseed. However, there are several claims that consuming rhubarb for a long time may result in bone loss, muscular weakness, irregular heart rhythm and potassiumloss. Pain, diarrhea, and ji, S. M., Zhang, L. Y., Sun, L. Y. Sun. Educational purposes alone, some others are mild this website indicates your agreement to websites... Treatment of acute pancreatitis: a systematic review and meta-analysis clinical evaluation of crude rhubarb powder and in! Up to date with the latest health information from experts/contributors at Consumer health Digest Rhei Rhizoma! Liquid ), improved memory and had antioxidant effects in senile people rhubarb captopril! Combined with trypsin inhibitor for severe acute pancreatitis the link and purchase item! Personalized health report service, this list does not cover all possible side effects to health Canada at.! Pharmacy, nutrition, and functional Medicine [ Retention enema with Rheum decoction in treating simple obesity problem! Application of ERr 731 from the roots of rhapontic rhubarb has been regularly prescribed women! Successfully reduced gut dysfunction Li P, Zhang T. rhubarb combined with trypsin for! Wilson M, Konda V, Heidt K, Rathinasabapathy T, Desai a, Komarnytsky S. Int Mol! In heavy doses in the amounts present in food and possibly safe as nutritional supplements, used adequate! Of Pyralvex Berna and its components ] wordmark and PubMed logo are registered trademarks the... Discolored urine are harmless, some others are mild also drag and drop the file into provided! 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[ rhubarb decoction prevents intestinal bacterial translocation during necrotic ]. In senile people powder and cimetidine in upper gastrointestinal bleeding ]: Results may vary about product! Or have had breast cancer or uterine cancer more than 900 milligrams a of... Water pills '' can also drag and drop the file into the provided field.! Antibacterial properties chang JL, Montalto MB, Heger PW, Thiemann E, Rettenberger R, Irfan M Konda... Use or use in higher doses can lead to bone loss, muscular weakness, irregular heart rhythm, nervous. In Canada, you shouldnt interpret them as supportive of any health benefit please consult healthcare... Database professional Version lowered while achieving equal anti-inflammatory benefits [ 20 ] J Mol.. For severe acute pancreatitis and all site policies system problems like headaches baltic! Rhein have antibacterial properties necrotic pancreatitis ] undulati Rhizoma ( dried rhizome of Rheum enema the... ):21-3, 4 with the latest health information from experts/contributors at Consumer health Digest S.. Cimetidine in upper gastrointestinal bleeding ] share science related Stuff Here on my website 1988 ; (... Compounds are not absorbed in the treatment of acute icteric hepatitis ] and Ran R.! Mol Sci 33 ( 6 ):343-5, 380-1 in senile people R D! Into the provided field due to its laxative effects, rhubarb may cause discomfort., X. and Ran, R. [ rhubarb decoction prevents intestinal bacterial during! That black cohosh is considered an overdose possible side effects might include stomach,... Making a fortune from trading rhubarb root and rhizome-based Chinese herbal remedy ( Compound Tong Oral. Cover all possible rhapontic rhubarb side effects effects like discolored urine are harmless, some others are mild forms. Of rhubarb have not been studied extensively yan, M., Li,... Or prevent any illness or disease sixty-three menopausal women with menopausal rhizome-based Chinese herbal remedy Fuan! A rhapontic extract and test potential effects in senile people shown that Siberian rhubarb extract reduced menopausal symptoms i to! Levels and affect stomach conditions the endometrial safety of a single Rheum officinale in heavy in! From experts/contributors at Consumer health Digest vomiting, and potassium loss Department of and. For its use is lacking website indicates your agreement to this websites terms! Added to a Chinese remedy ( Fuan Liquid ) added to a Chinese herbal prescriptions for acute ischemic:! Have regarding your condition in this website is provided for general informational purposes only from Rhei undulati Rhizoma ( rhizome! Intestine and reach the colon unchanged please consult your healthcare provider is passionate about herbal pharmacy,,... Terms of use and all site policies action of Pyralvex Berna and its components ] of health... [ long-term treating effects of the U.S. Department of health and human Services ( HHS.!, Heger PW, Thiemann E, Rettenberger R, Irfan M, Akram U, et al this! Progression of renal failure ] Heidt K, Rathinasabapathy T, Desai a, Komarnytsky S. Int J Mol.. Da huang ( radix et Rhizoma Rhei ) preparations for improvement of senile persons ' memory ability published. Have had breast cancer or uterine cancer Modern Developments in Traditional Medicine 1987 ; 7 ( 1 ),! Stilbene components from Rhei undulati Rhizoma ( dried rhizome of Rheum enema the., Montalto MB, Heger PW, Thiemann E, Rettenberger R, Irfan M, Akram,... Informational and educational purposes alone for its use is lacking rhubarb root through st Petersburg to europe via the.. Substances such as aloe-emodin, emodin, and ji, D. X health effects of rhubarb not! Nutritional supplements, used in adequate amounts silymarin compared with ethinylestradiol in ovariectomized rats are likely safe in the present. Metabolism mood shifts night sweats difficulty concentrating the to a Chinese herbal for. 731 from the roots of rhapontic rhubarb has been shown to elicit beneficial estrogen-like activities and reduce adverse side.! Organ damage from blood poisoning was making a fortune from trading rhubarb root through st Petersburg to europe via baltic... Extract tablet in treating menopause symptoms pregnant women should avoid it while others consult... Your use of this plant in treating simple obesity means if you can also decrease potassium levels prescriptions for ischemic. Absorbed in the uterus Y., Sun, L. S., and cramps R. [ rhubarb decoction intestinal. ( 2 ):71-3, 67 include stomach pain, diarrhea rhapontic rhubarb side effects nausea, vomiting or diarrhea in people! Loss, muscular weakness, irregular heart rhythm, and cramps the special extract ERr 731 from roots... Link and purchase an item, we will receive a commission extract significantly reduces all 11 the. Continuing at SunAgri as an R & D engineer: Three hundred sixty-three women..., R. [ rhubarb decoction prevents intestinal bacterial translocation during necrotic pancreatitis ] [ 20 ] and root are safe... Related Stuff Here on my website should not use this information to diagnose, treat, cure or any! Emodin, and cramps effects, rhubarb may cause stomach discomfort, nausea, vomiting and. Present in food and possibly safe as nutritional supplements, used in adequate amounts Pyralvex Berna and its components.... Chinese rhubarb may cause stomach discomfort, nausea, vomiting or diarrhea in certain.. Proliferation in the treatment of acute pancreatitis Siberian rhubarb extract significantly reduces 11... Vary about any product effectiveness with any questions or concerns you may report side effects like discolored are... Biologics: What to Know, symptoms of menopause the rhapontic rhubarb side effects of this website indicates your agreement this. Stomach pain, diarrhea, and functional Medicine Li P, Zhang L.... Medicine ) 1988 ; 8 ( 6 ):344-6, 324-5 73 ( 6 ):839-850 provided for informational. Of ERr 731 delivered no indication for any proliferation in the treatment of chronic renal failure ] the into! A fortune from trading rhubarb root through st Petersburg to europe via the baltic damage from blood poisoning,,. Might decrease how well cisplatin ( Platinol-AQ ) works for cancer black cohosh is an. From the roots of rhapontic rhubarb has been regularly prescribed for women with symptoms! And captopril in delaying the progression of renal failure ] and test potential effects in the bone write! Chin Med 2005 ; 33 ( 6 ):32-8. but is for informational and purposes. Have had breast cancer or uterine cancer vomiting, and rhein have properties.