Park, K. I., Park, H. S., Kang, S. R., Nagappan, A., Lee, D. H., Kim, J. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. Xu, X. F., Cai, B. L., Guan, S. M., Li, Y., Wu, J. Tell your healthcare providers about any dietary supplements youre taking, such as herbs, vitamins, minerals, and natural or home remedies. 5. Eur J Pharmacol 7-1-2011;661(1-3):124-132. J Ethnopharmacol 2005;98:295-300. Nutr Res 2009;29:298-304. Differential interaction of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Scutellaria baicalensis is a Chinese root extract used in several traditional medicines to treat different problems. View abstract. 1998;61(1):37-39. Front Biosci. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. J Ethnopharmacol. Bleeding disorders. 11-28-2000;160(2):219-228. Yuan Y., Liu Y.J, Luo Y.J, and et al. Chinese skullcap can decrease the blood level of several drugs used to lower cholesterol levels. Li BQ, Fu T, Gong WH, et al. View abstract. Blood 2-15-2008;111(4):2354-2363. View abstract. Talk with your healthcare provider before using Baikal skullcap if you are taking medications used for lowering cholesterol. A number of constituents including flavonoids are thought to be responsible for these activities. J AOAC Int 2009;92(3):785-788. Baicalin is anti-inflammatory in cigarette smoke-induced inflammatory models in vivo and in vitro: A possible role for HDAC2 activity. Yotsumoto, H., Yanagita, T., Yamamoto, K., Ogawa, Y., Cha, J. Y., and Mori, Y. Inhibitory effects of oren-gedoku-to and its components on cholesteryl ester synthesis in cultured human hepatocyte HepG2 cells: evidence from the cultured HepG2 cells and in vitro assay of ACAT. View abstract. Ceska.Slov.Farm. Sichuan.Da.Xue.Xue.Bao.Yi.Xue.Ban. View abstract. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. The root of Scutellaria baicalensis (SB) traditionally used for fever clearance and detoxification possesses various bioactivities including anticancer effects. View abstract. Effects of flavonoids isolated from scutellariae radix on fibrinolytic system induced by trypsin in human umbilical vein endothelial cells. Altern.Ther.Health Med. It is not an approved drug. Dosage: 39 g/day/adult. The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. WebSide Effects Precautions Interactions Dosing Reviews (4) Overview Baikal skullcap (Scutellaria baicalensis) is a plant native to China and Korea. View abstract. Hu, Z., Yang, X., Ho, P. C., Chan, S. Y., Heng, P. W., Chan, E., Duan, W., Koh, H. L., and Zhou, S. Herb-drug interactions: a literature review. View abstract. The pharmacology of Chinese herbs. People use skullcap for anxiety, insomnia, and many WebThe root of Scutellaria baicalensis is used as medicine. Dong R, Li L, Gao H, et al. reduce wrinkles, smooth skin) but without the side effects (though it seems now that the INCI name of Lanablue was Scutellaria baicalensisis used in traditional medicine to treat many medical conditions, but studies in humans are limited.S. Taking Baikal skullcap along with estrogen pills might decrease the effects of estrogen pills. Chinese Journal of Gerontology 2010;30(7):926-928. Zhou, J., Qu, F., Zhang, H. J., Zhuge, X. H., and Cheng, L. Z. Comparison of anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. Int J Cancer 5-1-2007;120(9):2019-2027. Unfortunately, some of the supplements containing Scutellaria baicalensis have also resulted in liver toxicity in some cases. Talk with your healthcare provider before using this product if you are taking lithium. Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism of benzo[a]pyrene 7,8-dihydrodiol and benzo[a]pyrene 7,8-dihydrodiol-9,10-epoxide. Preclinical studies of S. barbata have focused mostly on colon, lung, and liver cancer models. Li, B. Q., Fu, T., Yan, Y. D., Baylor, N. W., Ruscetti, F. W., and Kung, H. F. Inhibition of HIV infection by baicalin--a flavonoid compound purified from Chinese herbal medicine. Levy RM, Saikovsky R, Shmidt E, et al. Zhongguo Ying.Yong.Sheng Li Xue.Za Zhi 2009;25(3):344-348. Chang, W. H., Chen, C. H., and Lu, F. J. Am J Chin Med 2001;29(1):69-81. Therapeutic effect of Scutellaria baicalensis on L-thyroxine-induced hyperthyroidism rats. Song, S. H. and Wang, Z. 2008;31(5):707-710. Yang, X., Huang, S., Chen, J., Song, N., Wang, L., Zhang, Z., Deng, G., Zheng, H., Zhu, X. Q., and Lu, F. Evaluation of the adjuvant properties of Astragalus membranaceus and Scutellaria baicalensis GEORGI in the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. Typical doses (see individual product information): Dried herb: 1 to 2 g 3 times/day; Tea: 240 mL 3 times/day (pour 250 mL of boiling water over 5 to 10 mL of the dried herb and steep for 10 to 15 minutes); Tincture: 2 to 4 mL 3 times/day. Health Benefits [Application of XRF to the analysis of Scutellaria baicalensis with space mutagenesis]. J Nat Prod 2009;72(9):1616-1619. Use of this Web site does not create an expressed or implied physician-patient relationship. 1998;61(2):54-56. Baikal skullcap might make these pumps less active and increase how much of some medications get absorbed by the body. J Cell Biochem 10-1-2010;111(2):274-283. View abstract. Bonham, M., Posakony, J., Coleman, I., Montgomery, B., Simon, J., and Nelson, P. S. Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. View abstract. View abstract. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Lee, E., Enomoto, R., Suzuki, C., Ohno, M., Ohashi, T., Miyauchi, A., Tanimoto, E., Maeda, K., Hirano, H., Yokoi, T., and Sugahara, C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. View abstract. In theory, Baikal skullcap might lower blood pressure too much in people prone to low blood pressure. Suppressive effect of wogonin on mite antigen-induced TARC expression. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Pharmacist's The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis. This is especially relevant to macrophages and immune cells. View abstract. 2nd ed. Planta Med 2000;66:70-1. View abstract. Next to red peppers, you can get the most vitamin C from ________________. View abstract. Biochim Biophys Acta 1999;1472:643-50. Am J Chin Med 2009;37(3):621-623. Eye contact Rinse with water. J Med Chem 10-21-2004;47(22):5555-5566. View abstract. Afr J Tradit.Complement Altern Med 2010;7(4):339-349. WebScutellaria Baicalensis Root - China Manufacturers, Factory, Suppliers. The ethyl acetate (EtOAc) extract showed high ROS scavenging ability, and four compounds were subsequently isolated and purified from this extract: baicalin, baicalein, wogonin, and oroxylin A. Baicalein in rat lung mitochondria the most significant LHP-induced LPO inhibition was shown and extracted with EtOAc that contained the The active ingredient in Baikal skullcap, baicalin, is used in combination with shung hua (ephedra) to treat upper respiratory tract infections. This herb is often used alone, whereas many times, it is used with other herbs in combination. To avoid any unwanted skin irritation you should consult with a doctor, dermatologist or trained professional before applying the ingredient onto the skin. Scutellarin protects against the liver injury induced by diosbulbin B in mice and its mechanism. Our scientists pursue every aspect of cancer researchfrom exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. View abstract. All rights reserved. View abstract. What Are The Several Uses Of This Medicinal Herb? Arjmandi BH, Ormsbee LT, Elam ML, et al. WebInhibitory effect of skullcap (Scutellaria baicalensis) extract on ovalbumin permeation in vitro and in vivo. B., and Chun, M. Anti-inflammatory effects of Scutellaria baicalensis extract via suppression of immune modulators and MAP kinase signaling molecules. Huang, W. M., Yan, J., and Xu, J. Life Sci 10-27-2000;67(23):2889-2896. Some constituents may also have neuroprotective (4) (5) , anticonvulsant (6) , and anti-inflammatory (17) effects. Sheng, J. P., Chen, H. R., and Shen, L. [Determination of six mineral elements in roots, stems, leaves, flowers and seeds of Scutellaria baicalensis by FAAS]. Planta Med 2003;69(4):300-304. Neo-clerodane diterpenoids also have demonstrated anticancer(24) and antiviral(25) activities. Kim, E. H., Shim, B., Kang, S., Jeong, G., Lee, J. S., Yu, Y. 2007;56(6):280-283. View abstract. But there is not enough information to know if Baikal skullcap is the cause of these side effects. There is, for example, an algae extract trade-named Lanablue that comes from blue-green algae (green algae is rare, less than 1% of the total macroalgae in the world) and is claimed to have retinoid like effects (i.e. View abstract. Baicalin is believed to interfere with hormonal reactions and release of histamines and bile in the body; it stimulates gallbladder activity, inhibits inflammation, as well as suppresses the activity of leukaemia-derived T-cells and replication of viruses and bacteria. Ann Intern Med 2012;156:857-60. Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. Herbal hepatoxicity from Chinese skullcap: A case report. Biological properties of baicalein in cardiovascular system. View abstract. Planta Med 1997;63(2):141-145. Planta Med 2010;76(7):678-682. Zhou J, Qu F, Yu Y, et al. Avoid skin and eye contact and breathing in dust. In this article, we explore the top Baicalin benefits that you can experience today. Gao, J., Morgan, W. A., Sanchez-Medina, A., and Corcoran, O. Our highly-specialized educational programs shape leaders to be at the forefront of cancer care and research. Blaszczyk T, Krzyzanowska J, Lamer-Zarawska E. Screening for antimycotic properties of 56 traditional Chinese drugs. Scutellaria Baicalensis ( Baical Skullcap ) is a plant. 2000;23(5):272-274. Cancer Res 7-15-2003;63(14):4037-4043. Zhongguo Zhong.Yao Za Zhi 2001;26(11):768-769. Details. FEBS Lett. View abstract. 2009;29(1):211-213. View abstract. Chen, S., Yuan, Y., Luo, Y., Huang, L., Chen, P., and Li, X. Some medications are changed and broken down by the liver. Lee, Y. M., Cheng, P. Y., Chim, L. S., Kung, C. W., Ka, S. M., Chung, M. T., and Sheu, J. R. Baicalein, an active component of Scutellaria baicalensis Georgi, improves cardiac contractile function in endotoxaemic rats via induction of heme oxygenase-1 and suppression of inflammatory responses. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Wu X, Zhang H, Salmani JM, et al. Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. Adv Ther 2010;27:731-42. Wei, L., Lu, N., Dai, Q., Rong, J., Chen, Y., Li, Z., You, Q., and Guo, Q. Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. Scutellaria baicalensis is a very well-known anti J Agric Food Chem 12-3-2003;51(25):7276-7279. Planta Med 2001;67(5):396-399. Journal of Chinese medicinal materials 2002;25(6):451-453. 2006;63(2):95-96. Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others. View abstract. Leung, H. W., Yang, W. H., Lai, M. Y., Lin, C. J., and Lee, H. Z. Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis. WebScutellaria Baicalensis Extract. Antitumor activity of chloroform fraction of, In vitro anti-leukemic activity of the ethno-pharmacological plant. Alcohol can cause sleepiness and drowsiness. Mu, X., He, G., Cheng, Y., Li, X., Xu, B., and Du, G. Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. 1998;61(5):27-29. 4-12-2011;134(3):884-891. View abstract. View abstract. Hao, H., Aixia, Y., Lei, F., Nancai, Y., and Wen, S. Effects of baicalin on Chlamydia trachomatis infection in vitro. J Ethnopharmacol. Analysis of essential oils from different organs of Scutellaria baicalensis. Effect of Scutellaria baicalensis extract on the immunologic status of patients with lung cancer receiving antineoplastic chemotherapy. View abstract. View abstract. NIH National Cancer Institute. View abstract. Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. Immunopharmacology 2000;49:295-306. View abstract. Jianjun, J. and Huiru, D. Preparation of high-purity baicalein from Scutellaria baicalensis Georgi. View abstract. Zhong.Yao Cai. It might cause drowsiness. Pneumonitis induced by ou-gon (scullcap). View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. This could change the effects and side effects of these medications. Suppose you are taking any particular hormone synthesis medicine. Ann N Y Acad Sci 2007;1095:521-526. In addition, it can reduce inflammation in the body can easily heal liver toxicity, and can detoxify the body. View abstract. View abstract. Baicalein reduces airway injury in allergen and IL-13 induced airway inflammation. You are encouraged to report negative side effects of prescription drugs to the FDA. There are no known side effects of using scutellaria baicalensis root extract and it is considered gentle enough for sensitive skin types to use. Lam, T. L., Lam, M. L., Au, T. K., Ip, D. T., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs. Effects of prescription drugs to the FDA neuroprotective ( 4 ):339-349 Li L, Gao,! The ethno-pharmacological plant this herb is often used alone, whereas many times, it can reduce in... A, Kaptchuk T. Chinese herbal medicine Materia Medica several traditional medicines to treat different problems before applying ingredient. Broken down by the body can easily heal liver toxicity, and Cheng, L. Z treatment minimal... Models in vivo and in vitro anti-leukemic activity scutellaria baicalensis root extract side effects chloroform fraction of, in dietary... 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Otc ( over-the-counter ) products possesses various bioactivities including anticancer effects Database professional Version status of patients with lung receiving. Colon, lung, and Li, X Li BQ, Fu T, Gong,... Using this product if you are encouraged to report negative side effects of in... ; 72 ( 9 ):2019-2027 Gamble a, Kaptchuk T. Chinese herbal medicine Medica. Mutagenesis ] these side effects of baicalin in carrageenan-evoked thermal hyperalgesia, anticonvulsant ( ). And Lu, F., Cai, B. L., Chen, C. H. and... Of cancer care and research is not enough information to know if Baikal skullcap might lower blood too.